Practice Closure & Professional Transition Notice
Effective October 1, 2026, the clinical practice of the Naturopathic Medical Research Clinic is permanently closed.
Dr. Ray Pataracchia, ND (Inactive), has officially retired from clinical practice and is no longer accepting patients, providing treatment plans, or offering direct clinical care. For administrative inquiries, please contact info@nmrc.ca.
This website archive is for informational purposes only. Please do not use this website to self-diagnose or self-prescribe. If you are searching for a medical provider in your area, please see the website links provided in the FAQ section.
Foundations for Treatment Success
Two-time Nobel Laureate Linus Pauling defined Orthomolecular practice as “the preservation of health and the treatment of disease by varying the concentration of substances that are normally present in the body and are required for health.” Because this approach centers on biochemical individuality, the required daily health adjustments can be demanding. Highly customized protocols generally involve precise supplement timing, targeted nutrition, and careful tracking. Ultimately, successful outcomes within this framework rely on a strong therapeutic alliance—one rooted in mutual respect, clear communication, and dedicated patient compliance with their chosen healthcare provider.
Frequently Asked Questions (FAQ)
Response
A positive responder is a patient whose energy starts to lift and whose symptoms dissipate in layers. Positive responders have symptoms that can improve quickly or incrementally depending on how ingrained the biochemical profile is and how compliant they are.
Responses vary depending on biochemical severity and compliance.
Please see the peer reviewed case study series Orthomolecular Treatment Response published in The Journal of Orthomolecular Medicine in 2010. Advanced functional medicine continues to evolve in its ability to address advanced health conditions.
Orthomolecular Treatment Approaches
Everyone has a unique biological pattern and the right lab tests can help determining how best to ‘target’ the nutritional treatment. Targeted blood testing and unwashed hair mineral-metal analysis are for example helpful in determining a meaningful treatment approach (as they factor in well over 100 fundamental metabolic trends).
Primary orthomolecular protocols focus on the normalization of pivotal lab trends with the goal of optimal reference range balancing. A toolbox of primary treatment options should include the balancing of copper 2+ toxicity, copper 1+ deficiency, zinc deficiency, heavy metal overload (copper, mercury, lead, …), niacin dependency/deficiency, and food intolerance. Other metabolic trends that are the important to address and can be considered primary (varies per case) include overall mineral imbalance, zinc-B6-manganese deficiency (pyroluria), inadequate food intake, cell function imbalance (fast/slow oxidation, mitochondrial compromise, …), sugar imbalance, iron imbalance, inflammation, and thyroid-adrenal imbalance.
To normalize multiple layers of imbalance simultaneously and safely, core primary minerals/vitamins that are given at the right dose are essential to biochemical balancing. Correcting zinc imbalance for example, will help to support the 200+ metabolic pathways that zinc is involved in (brain, heart and digestive health, etcetera).
Health Conditions Amenable to Orthomolecular Treatment
Conditions and health concerns that are often amenable to orthomolecular treatment include: fatigue (the top chief complaint in clinical practice), mental health (depression, anxiety, bipolar, ADHD, schizophrenia, PTSD), insomnia, digestive disorders/symptoms, thyroid imbalances, allergies, weight problems, aging, circulatory conditions, female/male health conditions, poor academic/work performance, concussion syndrome, and more.
Orthomolecular Provider Links
Here are some links to help you find an Orthomolecular medical provider local to you: Classic Orthomolecular Directory, Psychiatry Redefined, and Orthomolecular.org Practitioner Directory.
Nourished Minds - Healthy Lives
Specialized testing, diet, lifestyle modification and health treatments that focus on your individual needs can support both your body and your mind.
Top Clinic Pages
Schizophrenia strikes hard and fast in our teen and young adult population. Based on 25 years of clinic outcomes, 80% of cases treated with advanced clinical nutrition experience mild to profound response.
Diet and supplementary nutrition that corrects body systems imbalances can improve general or mental health. Here are some of the top nutrient imbalances.
This peer-reviewed case series puts a real person perspective on the potential of advanced clinical nutrition. Here we look at 5 cases with a timeline of landmark improvements.
The suffering of patients with depression, anxiety, bipolar depression, ADD and OCD is immense. This article looks at the role of advanced clinical nutrition in their treatment.
You are only as old as your arteries. Here we look at how strengthening your vascular integrity and overall vascular health is a key factor in healthy aging.
Naturopathic Medical Research Clinic Articles…
Opting for Advanced Niacin Therapy in First Episode Schizophrenia
Advanced Niacin Therapy offers hope and aims to alleviate the devastation that patients and their families experience with this condition that we call Schizophrenia. ADVANCED NIACIN THERAPY Advanced Niacin Therapy is an orthomolecular protocol tailored for...
High Protein Intake for Weight Loss & Heart Health
Did you know that high protein intake can help you lose weight and improve cardiovascular health? Research now suggests that high protein intake can help us maintain healthier weight while sustaining lean body mass. High protein low carbohydrate diets are associated...
Advanced Niacin Therapy for Severe Stress & PTSD
Did you know that vitamin B3 can be considered one of the best nutrients available for mild to severe states of stress including PTSD? … If you live in Toronto, Mississauga, Oakville, Milton, Burlington, Hamilton, or Niagara you might consider advanced niacin therapy...
Vitamin B3 – One of the Best Nutrients for Longevity
Did you know that vitamin B3 is one of the best longevity nutrients available? … If you live in Toronto, Mississauga, Oakville, Milton, Burlington, Hamilton, or Niagara you might consider our advanced clinical nutrition approach for healthy aging and longevity. There...
Case Report* of Positive Treatment Response in Schizophrenia
Did you know that “Schizophrenia Ranks among the top 10 causes of disability in developed countries worldwide”? … If you hear voices or have delusional thoughts and you live in Toronto, Mississauga, Oakville, Milton, Burlington, Hamilton or Niagara, you should...
Nutritional Treatment for Schizophrenia
Did you know that early treatment of schizophrenia has its merits from a conventional and nutritional treatment perspective … If you hear voices or have delusional thoughts and you live in Toronto, Mississauga, Oakville, Milton, Burlington, Hamilton or Niagara, you...
Hashimoto’s (Autoimmune Hypothyroidism): Advanced Orthomolecular Perspectives
Did you know that Hashimoto’s (autoimmune hypothyroid) has a genetic component and commonly affects women 30-50 years old? … If you live in Toronto, Mississauga, Oakville, Milton, Burlington, Hamilton, or Niagara you should consider our advanced clinical nutrition...
ADD and ADHD: An Empirical Nutrition Approach
Do you suspect your son or daughter has ADD/ADHD/hyperactivity? … If so, you should consider our Empirical Nutrition Approach. If you live in Ontario, Toronto, GTA, Niagara, Hamilton, Burlington, or Western New York you are in our catchment area. An Empirical...
Back to School: Eating Paleo to Improve Behavior
Do your kids eat a solid breakfast before leaving for school? … If not, you may consider a Paleo breakfast routine. A Paleo breakfast is associated with better behavior functioning. If you live in Southern Ontario, Toronto (GTA), Niagara, Hamilton, Burlington, or...






